PANCREATIC CANCER

More in PANCREATIC CANCER

• Chemotherapy affects immune cell landscape in pancreatic cancer: Study

  Published in the journal Nature Communications online Feb.13, the study analyzed more than 139,000 tumor cells collected from 27 patients with pancreatic ductal adenocarcinoma (PDAC), a hard to detect and treat cancer, with only 12 per cent of patients surviving longer than five years after diagnosis. According to researchers, a strong immune response to tumors in the tissue surrounding them is critical to shrinking these tumors in the pancreas.

  

• Pancreatic cancer rates rising faster in females than in males: Study

  In this study, investigators combed data from the National Program of Cancer Registries (NCPR) database, which represents approximately 64.5 per cent of the US population, on patients diagnosed with pancreatic cancer between 2001 and 2018.

  

• Study reveals four-drug chemotherapy regimens treat metastatic pancreas cancer

  The four-drug regimen consisted of liposomal irinotecan, 5-fluorouracil/leucovorin and oxaliplatin - together referred to as NALIRIFOX. The two-drug therapy consisted of nab-paclitaxel and gemcitabine.

  

• Tumor initiation in pancreatic cancer driven by stress-tolerant cells: Study

  Tumor-initiating cells (TIC) play a major role in the formation, recurrence and metastatic spread of tumors. What sets them apart from other cancer cells is their resilience to these early substandard conditions. Like cacti in a desert, they can adapt to the harsh environment and set the scene for further tumor progression.

  

• Triple immunotherapy combination might be possible treatment for pancreatic cancer: Study

  In this study, they found that neutralizing several distinct immunosuppressive mechanisms of the TIME dramatically improved survival rates in laboratory models, pointing to a potential treatment option for this notoriously lethal and unresponsive cancer.

  

• Japanese biotech firm uses tiny worms in test for pancreatic cancer

  Users send a urine sample through a special mail pouch to a lab, where it is put in a petri dish with a species of nematodes. The creatures, known scientifically as C. elegans, have olfactory senses much more powerful than dogs, the company says, and they follow their nose toward cancer cells. That makes the 1-milimetre long animals a potent diagnostic tool.

  

• Pancreatic cancer is a silent disease but new study has found a way to diagnose it up to three years in advance

  The results suggest that unexplained weight loss, mainly in people with diabetes (but not exclusively) should be treated with suspicion. Also, increasing glucose levels, especially in people without weight gain, should be considered a potential red flag for pancreatic cancer.

  

• Researchers reveal failures in process of detecting pancreatic cancer

  Results revealed over a third (36%) of PIPC cases were potentially avoidable, demonstrating a poor detection rate for a cancer that has alarming patient outcomes

  

• Survival rates for deadliest types of pancreatic cancer vary: Study

  The relative amounts of cleaved versus non-cleaved Col 1 in the human PDAC stroma or connective tissue strongly affect patient survival after surgical resection. Patients whose tumours were enriched in cleaved Col 1 and whose cancerous cells expressed high levels of DDR1 fared poorly, with most succumbing to their disease within two years of surgery.

  

• Study uncovers link between inflammation and pancreatic cancer development

  According to the study, pancreatic cells display an adaptive response to repeated inflammatory episodes that initially protects against tissue damage but can promote tumour formation in the presence of mutant KRAS.

  

• Fortis doctors perform India's 1st Whipple surgery on pregnant woman

  Fahima, was five and a half months pregnant when she was diagnosed with pancreatic cancer. On account of her pregnancy, she could also not undergo chemotherapy.