IMMUNE CHECKPOINT BLOCKADE

Immunotherapy was meant to defeat cancer - what happened to the great promise?

The immune system is the body's most powerful weapon against cancer and infection. For a cancer cell, surviving long enough to divide and eventually form a lump or tumour is the result of a brutal Darwinian process. To reach this point, cancer must adapt, hiding from immune detection and co-opting patients' immune machinery to betray its original programming and instead protect the cancer.